Picralima Nitida could be a plant genus in the family Apocynaceae, first described as a genus in 1896. It includes just one known species, Picralima Nitida, naturally to Tropical Africa. Picralima Nitida or you can say Akuamma is a tree. The dries seeds of this tree were used in old times as medicine throughout West Africa, mainly in Ghana, the Ivory Coast, and Nigeria. The seeds of this plant are crushed or powdered, consumed orally, and are particularly used for the treatment of diarrhea malaria, and also can be used as a painkiller.
The tree generates the alkaloids pericine and akuammine, among several others. An enterprising Ghanaian hospital started manufacturing and selling the 250mg standardized capsules of the powered Picralima Nitida, which became a vastly used palliative. This then led the researchers to try to find the active component of the seeds. People can order Picralima Nitida online if they want.
Picralima Nitida seeds include a complex mixture of alkaloids generating antipyretic and anti-inflammatory symptoms and analgesia in animal studies. Many of these were shown to bind to the opioid receptors with a weak affinity in vitro and include two compounds, akuammidine and akuammigine, that were said to be opioid agonists. At the latest, it has been shown that an additional constitutive analog has a potent activity as a kappa-opioid receptor agonist. Picralima Nitida is available online. So you can buy Picralima Nitida online.
Picralima Nitida could be the only species of the genus Picralima. This belongs to the Hunterieae tribe of the apocynaceae family. The tree is majorly distributed in the high deciduous forest of West-Central Africa from the Ivory Coast to Cameroons and exceeding to the Congo basin and Uganda.